The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Jul. 25, 2011
Applicants:
Marius Hoener, Basel, CH;
Susanne Raab, Aesch BL, CH;
Celine Risterucci, Mulhouse, FR;
Sabine Sewing, Basel, CH;
Inventors:
Marius Hoener, Basel, CH;
Susanne Raab, Aesch BL, CH;
Celine Risterucci, Mulhouse, FR;
Sabine Sewing, Basel, CH;
Assignee:
HOFFMANN-LA ROCHE INC., Nutley, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5513 (2006.01); A61K 31/422 (2006.01); A61K 31/4168 (2006.01); A61K 31/455 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/4439 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/40 (2006.01); A61K 31/421 (2006.01); A61K 31/5375 (2006.01); A61K 31/551 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5513 (2013.01); A61K 9/1623 (2013.01); A61K 9/2018 (2013.01); A61K 9/4858 (2013.01); A61K 31/40 (2013.01); A61K 31/4168 (2013.01); A61K 31/421 (2013.01); A61K 31/422 (2013.01); A61K 31/4439 (2013.01); A61K 31/455 (2013.01); A61K 31/506 (2013.01); A61K 31/5375 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); C07D 413/12 (2013.01);
Abstract
The present invention relates to a pharmaceutical combination for the treatment of schizophrenia and acute manic episodes associated with bipolar disorders, which comprises a compound which is active on a trace amine-associated receptor 1 (TAAR1 agonist) and an antipsychotic drug. This combination can reduce metabolic side effects which appear if using an antipsychotic drug alone.