The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Mar. 18, 2013
Applicant:

Vascular Therapies Llc, New York, NY (US);

Inventors:

Sriram Iyer, New York, NY (US);

Nicholas Kipshidze, New York, NY (US);

Victor Nikolaychik, Thiensville, WI (US);

Gary Roubin, Jackson, WY (US);

Assignee:

VASCULAR THERAPIES, INC., Cresskill, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 15/16 (2006.01); A61F 13/00 (2006.01); A61F 2/00 (2006.01); A61K 38/00 (2006.01); A61K 38/13 (2006.01); A61K 31/727 (2006.01); A61K 9/70 (2006.01); A61B 17/00 (2006.01); A61K 31/436 (2006.01); A61K 31/4745 (2006.01); A61L 31/04 (2006.01); A61L 31/16 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7007 (2013.01); A61B 17/0057 (2013.01); A61K 31/436 (2013.01); A61K 31/4745 (2013.01); A61L 31/044 (2013.01); A61L 31/16 (2013.01); A61B 2017/00641 (2013.01); A61B 2017/00659 (2013.01); A61B 2017/00893 (2013.01); A61L 2300/416 (2013.01);
Abstract

Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses.


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