The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2015

Filed:

Apr. 21, 2009
Applicants:

Jay Lichter, Rancho Santa Fe, CA (US);

Andrew M. Trammel, Olathe, KS (US);

Fabrice Piu, San Diego, CA (US);

Luis A. Dellamary, San Marcos, CA (US);

Qiang YE, San Diego, CA (US);

Carl Lebel, Malibu, CA (US);

Michael Christopher Scaife, Los Altos, CA (US);

Jeffrey P. Harris, La Jolla, CA (US);

Inventors:

Jay Lichter, Rancho Santa Fe, CA (US);

Andrew M. Trammel, Olathe, KS (US);

Fabrice Piu, San Diego, CA (US);

Luis A. Dellamary, San Marcos, CA (US);

Qiang Ye, San Diego, CA (US);

Carl Lebel, Malibu, CA (US);

Michael Christopher Scaife, Los Altos, CA (US);

Jeffrey P. Harris, La Jolla, CA (US);

Assignees:

OTONOMY, INC., San Diego, CA (US);

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0046 (2013.01); A61K 9/06 (2013.01); A61K 9/14 (2013.01);
Abstract

Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.


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