The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Mar. 14, 2013
Applicants:
Roger Kingdon Craig, Cheshire, GB;
Franklin Gerardus Grosveld, Rotterdam, NL;
Richard Wilhelm Janssens, Rotterdam, NL;
Marinus Johannes Van Haperen, Prinsenbeek, NL;
Inventors:
Roger Kingdon Craig, Cheshire, GB;
Franklin Gerardus Grosveld, Rotterdam, NL;
Richard Wilhelm Janssens, Rotterdam, NL;
Marinus Johannes Van Haperen, Prinsenbeek, NL;
Assignee:
ERASMUS UNIVERSITY MEDICAL CENTER, Rotterdam, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01); A01K 67/027 (2006.01); C07K 16/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0276 (2013.01); A01K 67/0278 (2013.01); A01K 2217/072 (2013.01); A01K 2217/15 (2013.01); A01K 2217/206 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); C07K 16/00 (2013.01); C12N 15/8509 (2013.01);
Abstract
A transgenic non-human mammal containing a heterologous lambda light chain gene locus, and/or a heterologous kappa light chain gene locus, and/or a heterologous heavy chain gene locus, each of which can re-arrange so that immunoglobulin heavy and light chain genes are formed and expressed in B-cells following antigen challenge.