The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Mar. 01, 2011
Applicants:

David D. Halbert, Colleyville, TX (US);

George Poste, Cave Creek, AZ (US);

Michael Klass, Oro Valley, AZ (US);

David Spetzler, Scottsdale, AZ (US);

Traci Pawlowski, Laguna Niguel, CA (US);

Daniel Holterman, Phoenix, AZ (US);

Inventors:

David D. Halbert, Colleyville, TX (US);

Christine Kuslich, Paradise Valley, AZ (US);

George Poste, Cave Creek, AZ (US);

Michael Klass, Oro Valley, AZ (US);

David Spetzler, Scottsdale, AZ (US);

Traci Pawlowski, Laguna Niguel, CA (US);

Andrea Tasinato, Gimel, CH;

Daniel Holterman, Phoenix, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); C12Q 1/6883 (2013.01); G01N 33/57484 (2013.01); G01N 33/6872 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); G01N 2333/705 (2013.01); G01N 2800/52 (2013.01); G01N 2800/60 (2013.01);
Abstract

Biomarkers can be assessed for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, or the stage or progression of a disease. Circulating biomarkers from a bodily fluid can be used in profiling of physiological states or determining phenotypes. These include nucleic acids, protein, and circulating structures such as vesicles. Biomarkers can be used for theranostic purposes to select candidate treatment regimens for diseases, conditions, disease stages, and stages of a condition, and can also be used to determine treatment efficacy. The biomarkers can be circulating biomarkers, including vesicles and microRNA.


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