The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Dec. 22, 2004
Applicants:

Roger J. Greenwald, Holley, NY (US);

James M. Zavislan, Pittsford, NY (US);

Inventors:

Roger J. Greenwald, Holley, NY (US);

James M. Zavislan, Pittsford, NY (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G02B 21/34 (2006.01); G01N 21/03 (2006.01); B01L 3/00 (2006.01); G02B 21/00 (2006.01); G01N 1/36 (2006.01);
U.S. Cl.
CPC ...
G01N 21/0303 (2013.01); B01L 3/508 (2013.01); G02B 21/0028 (2013.01); G02B 21/34 (2013.01); B01L 2300/043 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0672 (2013.01); B01L 2300/0822 (2013.01); B01L 2400/0683 (2013.01); G01N 1/36 (2013.01); G01N 2021/0339 (2013.01); G01N 2021/0342 (2013.01); G01N 2021/0364 (2013.01);
Abstract

A tray or holder for tissue specimens, especially of excised tissue, such as biopsied specimens, is used with a confocal imaging system. The tray may be disposable after imaging of the specimen carried therein or may archive the specimen. A window supports the specimen. Clamps mounted inside the tray restrain the tissue. A compliant bag is mounted outside the tray on one side of a window of the tray on which the specimen is disposed. During imaging the specimen is immersed in a liquid contained in the tray having an index of refraction which closely matches the index of refraction of the tissue. The bag also contains an index matching liquid preferably having the same index as the liquid in the tray. Selecting an immersion liquid, which equals the refractive index of the near surface tissues, minimizes wavefront distortion which may result from an effectively corrugated surface of the specimen.


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