The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Jan. 31, 2012
Applicants:

Ming-chou Lee, San Juan Capistrano, CA (US);

Sergey V. Voronov, Sharon, MA (US);

Laurence R. Mccarthy, Great Falls, VA (US);

Lilly I. Kong, Covina, CA (US);

Vesselin Tenkov Diankov, Franklin, MA (US);

Inventors:

Ming-Chou Lee, San Juan Capistrano, CA (US);

Sergey V. Voronov, Sharon, MA (US);

Laurence R. McCarthy, Great Falls, VA (US);

Lilly I. Kong, Covina, CA (US);

Vesselin Tenkov Diankov, Franklin, MA (US);

Assignee:

Qiagen Mansfield, Inc., Mansfield, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); C12Q 1/6851 (2013.01);
Abstract

Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.


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