The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Jan. 19, 2006
Applicants:

Tobias Walker, Tübingen, DE;

Hans-peter Wendel, Balingen, DE;

Inventors:

Tobias Walker, Tübingen, DE;

Hans-Peter Wendel, Balingen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61L 27/34 (2006.01); A61L 31/10 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61L 27/34 (2013.01); A61L 31/10 (2013.01); C12N 15/1135 (2013.01); A61K 48/00 (2013.01); C12N 2310/14 (2013.01);
Abstract

The present invention relates to a nucleic acid molecule, a genetic construct, siRNA molecules and a composition which comprises the nucleic acid molecule and/or the genetic construct and/or the siRNA molecules and can be used for inhibition of the expression of endothelial adhesion molecules. The invention also relates to a device, which is coated with the aforementioned molecules, the composition or the construct, or contains them. The present invention further relates to a corresponding use of the nucleic acid molecule, of the genetic construct or of the siRNA molecules and a method of inhibition of the expression of adhesion molecules and a method of vessel grafting, lung transplantation, treatment of lung transplants, and a method of treatment of the open heart within the scope of cardioplegia.


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