The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Mar. 30, 2009
Applicants:
Keith Bjornson, Newark, CA (US);
Sonya Clark, Oakland, CA (US);
Insil Park, Fremont, CA (US);
Fred Christians, Los Altos Hills, CA (US);
Inventors:
Keith Bjornson, Newark, CA (US);
Sonya Clark, Oakland, CA (US);
Insil Park, Fremont, CA (US);
Fred Christians, Los Altos Hills, CA (US);
Assignee:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1276 (2013.01); C12N 9/1252 (2013.01); C12P 19/34 (2013.01); C12Q 1/6869 (2013.01);
Abstract
Provided are compositions comprising modified DNA polymerases that exhibit improved photostability compared to the parental polymerases from which they were derived. Provided are methods for generating enzymes, such as DNA polymerases, with the aforementioned phenotype. Provided are methods of using polymerases with increased resistance to photodamage to make a DNA or to sequence a DNA template.