The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Dec. 13, 2007
Applicants:

Smadar Cohen, Beer Sheva, IL;

Mona Dvir-ginzberg, Jerusalem, IL;

Inventors:

Smadar Cohen, Beer Sheva, IL;

Mona Dvir-Ginzberg, Jerusalem, IL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12P 21/04 (2006.01); C12M 1/00 (2006.01); A01N 1/00 (2006.01); A01N 1/02 (2006.01); C12N 5/071 (2010.01); A61L 27/20 (2006.01); A61L 27/38 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0671 (2013.01); A61L 27/20 (2013.01); A61L 27/3813 (2013.01); A61L 27/3839 (2013.01); A61L 27/56 (2013.01); C12N 2500/25 (2013.01); C12N 2500/36 (2013.01); C12N 2500/38 (2013.01); C12N 2501/11 (2013.01); C12N 2501/39 (2013.01); C12N 2533/74 (2013.01);
Abstract

The present invention relates to bioresorbable scaffolding for tissue regeneration or repair. The present invention describes an epithelial organoid comprising an aggregate of epithelial cells predominantly expressing markers associated with differentiated cell types, and an aggregate which assumes a structure or performs a function associated with an epithelial organ or a fragment thereof. The present invention also provides a method of treating a subject in need of repair or replacement of an organ or a portion thereof; and/or a method of treating a subject with a disease or disorder which impairs or abrogates a liver, kidney, pancreas, thyroid or pituitary function. The present invention also describes an epithelial graft or artificial organ comprising spheroids, organoids or a combination thereof, and a kit for implantable epithelial graft formation comprising organoids.


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