The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Dec. 08, 2006
Applicants:

Hergen Spits, Amsterdam, NL;

Ferenc A. Scheeren, Kaatsheuvel, NL;

Tim Beaumont, Ouderkerk a/d Amstel, NL;

Sean A. Diehl, Shelburne, VT (US);

Inventors:

Hergen Spits, Amsterdam, NL;

Ferenc A. Scheeren, Kaatsheuvel, NL;

Tim Beaumont, Ouderkerk a/d Amstel, NL;

Sean A. Diehl, Shelburne, VT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0781 (2010.01); C12N 15/63 (2006.01); C12N 15/64 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0635 (2013.01); C07K 16/00 (2013.01); C12N 2501/23 (2013.01); C12N 2501/52 (2013.01); C12N 2501/60 (2013.01); C12N 2502/99 (2013.01); C12N 2510/02 (2013.01); C12N 2510/04 (2013.01);
Abstract

The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.


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