The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Nov. 25, 2009
Applicants:

Zeev Pancer, Baltimore, MD (US);

Roy A. Mariuzza, Chevy Chase, MD (US);

Satoshi Tasumi, Hamamatsu, JP;

Carlos A. Velikovsky, Bethesda, MD (US);

Inventors:

Zeev Pancer, Baltimore, MD (US);

Roy A. Mariuzza, Chevy Chase, MD (US);

Satoshi Tasumi, Hamamatsu, JP;

Carlos A. Velikovsky, Bethesda, MD (US);

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/08 (2006.01); C07K 14/715 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7158 (2013.01); C12N 15/1037 (2013.01); C40B 40/08 (2013.01);
Abstract

The present invention relates to a Yeast Surface Display (YSD) vector for expression of VLR proteins by yeast, wherein the vector includes nucleotide sequences encoding segments of yeast flocculation proteins Flo1p, such as the leader and C-terminal segments, a homologous recombinant cassette and a geneticin/kanamycin resistance gene. The vector can be used for expression of VLR that may be effective in diagnostic applications (e.g., protein chip, immunohistochemistry, flow cytometry), immunoaffinity purification, and for engineering novel fusion proteins.


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