The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Oct. 27, 2011
Toshiaki Ohtsuka, Saitama, JP;
Takeshi Takizawa, Tokyo, JP;
Akiko Oguni, Tokyo, JP;
Tatsuji Matsuoka, Tokyo, JP;
Hiroko Yoshida, Tokyo, JP;
Yumi Matsui, Tokyo, JP;
Toshiaki Ohtsuka, Saitama, JP;
Takeshi Takizawa, Tokyo, JP;
Akiko Oguni, Tokyo, JP;
Tatsuji Matsuoka, Tokyo, JP;
Hiroko Yoshida, Tokyo, JP;
Yumi Matsui, Tokyo, JP;
Daiichi Sankyo Company, Limited, Tokyo, JP;
Abstract
The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies.