The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Nov. 17, 2006
Applicants:

Steven D. Goodman, Redondo Beach, CA (US);

Olga Kay, Los Angeles, CA (US);

Wenyuan Shi, Los Angeles, CA (US);

Fengxia Qi, Oklahoma City, OK (US);

Inventors:

Steven D. Goodman, Redondo Beach, CA (US);

Olga Kay, Los Angeles, CA (US);

Wenyuan Shi, Los Angeles, CA (US);

Fengxia Qi, Oklahoma City, OK (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); A61K 8/60 (2006.01); A61Q 11/00 (2006.01); A61Q 17/00 (2006.01); C12N 1/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/00 (2013.01); A61K 8/60 (2013.01); A61Q 11/00 (2013.01); A61Q 17/005 (2013.01); C12N 1/00 (2013.01);
Abstract

Methods for selectively manipulating a growth rate of a selected bacterium comprising the step of contacting the selected bacterium with a predetermined amount of a quorum sensing molecule to affect a change in the growth rate of the selected bacterium, wherein the quorum sensing molecule is species specific, and the change in the growth rate is dependent on the amount of quorum sensing molecule in a dose-dependent fashion. Also provided are methods for treating or protecting against bacterial infections by utilizing the dose-dependent response of bacterial quorum sensing systems. The methods can be applied to a wide range of bacteria species including, and. Compositions, medicaments and oral formulations for use with the methods are also disclosed.


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