The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Sep. 14, 2012
Applicants:

Wesley Peter Blackaby, Saffron, GB;

Martin DE Kort, Oss, NL;

Mark Enthoven, Oss, NL;

Paul Stuart Hinchliffe, Saffron, GB;

Christian Bernard Matthijs Poulie, Oss, NL;

Cornelis Marius Timmers, Oss, NL;

Saskia Verkaik, Oss, NL;

Inventors:
Assignee:

Merck Sharp & Dohme B.V., BN Haarlem, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 31/4745 (2006.01); A61K 31/4375 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61K 31/4375 (2013.01); A61K 31/4745 (2013.01); C07D 471/04 (2013.01);
Abstract

The invention relates to FSH receptor antagonist according to general formula (I) or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.


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