The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Aug. 13, 2012
Applicants:

Rajan Anand, Westfield, NJ (US);

Vincent J. Colandrea, North Brunswick, NJ (US);

Maud Reiter, Geneva, CH;

Petr Vachal, Summit, NJ (US);

Aaron Zwicker, New Haven, CT (US);

Jonathan E. Wilson, Summit, NJ (US);

Fengqi Zhang, Edison, NJ (US);

Kake Zhao, Westfield, NJ (US);

Inventors:

Rajan Anand, Westfield, NJ (US);

Vincent J. Colandrea, North Brunswick, NJ (US);

Maud Reiter, Geneva, CH;

Petr Vachal, Summit, NJ (US);

Aaron Zwicker, New Haven, CT (US);

Jonathan E. Wilson, Summit, NJ (US);

Fengqi Zhang, Edison, NJ (US);

Kake Zhao, Westfield, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/498 (2006.01); C07D 241/42 (2006.01); C07D 409/06 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 409/06 (2013.01); A61K 31/498 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 241/42 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01);
Abstract

Compounds having the structure of Formula Ia, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and may be useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis.


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