The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Mar. 22, 2013
Applicants:

GE Healthcare Limited, Buckinghamshire, GB;

GE Healthcare As, Oslo, NO;

Inventors:

Anthony Eamon Storey, Lincs, GB;

Clare Louise Jones, Amersham, GB;

Denis Raymond Christophe Bouvet, Belfort, FR;

Nicholas Lasbistes, Surrey, GB;

Steven Michael Fairway, Oslo, NO;

Lorenzo Williams, Oslo, NO;

Alexander Mark Gibson, Amersham, GB;

Robert James Nairne, Amersham, GB;

Farhad Karimi, Mansfield, MA (US);

Bengt Langstrom, Uppsala, SE;

Assignees:

GE Healthcare Limited, Buckinghamshire, GB;

GE Healthcare AS, Oslo, NO;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/66 (2006.01);
U.S. Cl.
CPC ...
C07D 277/66 (2013.01);
Abstract

The invention relates to a process for preparation of a compound of formula (I): Ris selected from Calkyl, Calkenyl, and Calkynyl;which comprises:(i) reaction with fluoride, suitably [F]fluoride, of a corresponding compound of formula (II): wherein Ris selected from hydrogen, Calkyl, Chaloalkyl, Caryl, Carylalkyl, —(CHCHO)—CHwherein q is an integer of from 1 to 10;Ris as defined for the compound of formula (I); andRis a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed.


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