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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9125970 B1

PDFFull Text
Date of Patent:
Sep. 08, 2015

Filed:

Sep. 19, 2013

Adhesive composition for carrying therapeutic agents as delivery vehicle on coating applied to vascular grafts

Applicant:

The University of Tennessee Research Foundation, Knoxville, TN (US);

Inventors:

Omran R. Abul-Khoudoud, Germantown, TN (US);

Catherine Cagiannos, Cincinnati, OH (US);

Waldemar Derijk, Germantown, TN (US);

Timothy C. Fabian, Memphis, TN (US);

Lisa Jennings, Memphis, TN (US);

Assignee:

THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, Knoxville, TN (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Rachael E Bredefeld

Int. Cl.
CPC ...
A61L 27/16 (2006.01); A61L 27/54 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01); A61L 27/34 (2006.01); A61L 33/00 (2006.01); A61K 31/436 (2006.01); A61F 2/07 (2013.01); A61F 2/82 (2013.01); C08L 27/18 (2006.01); C08L 33/10 (2006.01); A61L 31/04 (2006.01);
U.S. Cl.
CPC ...
A61L 27/34 (2013.01); A61K 31/436 (2013.01); A61L 27/16 (2013.01); A61L 27/54 (2013.01); A61L 31/048 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61L 2300/404 (2013.01); A61L 2300/41 (2013.01); A61L 2300/416 (2013.01); A61L 2300/42 (2013.01);
Abstract

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.

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