The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Oct. 15, 2012
Applicant:

GE Healthcare Limited, Buckinghamshire, GB;

Inventors:

Rajiv Bhalla, St. Lucia Brisbane, AU;

Anthony Wilson, Waddesdon, GB;

Imtiaz Khan, Amersham, GB;

Janne Brown, Amersham, GB;

Assignee:

GE Healthcare Limited, Buckinghamshire, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 227/16 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01); C07C 319/14 (2006.01); C07C 303/30 (2006.01); C07D 451/02 (2006.01); C07C 67/10 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0406 (2013.01); A61K 51/0448 (2013.01); A61K 51/0455 (2013.01); C07B 59/001 (2013.01); C07C 67/10 (2013.01); C07C 227/16 (2013.01); C07C 303/30 (2013.01); C07C 319/14 (2013.01); C07D 451/02 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention provides a method for the synthesis ofF-labelled biomolecules, which is amenable to automation. The present invention also provides a cassette for automating the method of the invention. The method of the present invention provides numerous advantages over the prior art methods. One less purification step is required as compared with known methods. Also, one less reagent is required as a particular reagent is employed in two different steps. The chemistry process is thereby simplified, the cost of goods is reduced and the burden of validation and documentation of reagents required for GMP clinical production is minimized.


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