The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Sep. 23, 2014
Applicant:
Kempharm, Inc., Coralville, IA (US);
Inventors:
Travis Mickle, Celebration, FL (US);
Sven Guenther, Coralville, IA (US);
Christal Mickle, Celebration, FL (US);
Assignee:
KemPharm, Inc., Coralville, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/19 (2006.01); A61K 47/48 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48038 (2013.01); A61K 31/44 (2013.01); A61K 31/485 (2013.01);
Abstract
The presently described technology provides phenylethanoic acid, phenylpropanoic acid, phenylpropenoic acid, a salt thereof, a derivative thereof or a combination thereof chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs or compositions of hydrocodone which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.