The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Dec. 19, 2012
Applicant:
Depuy Mitek, Llc, Raynham, MA (US);
Inventors:
Brooks J. Story, Franklin, MA (US);
M. E. Liesbeth Brown, West Newton, MA (US);
Francois Binette, San Francisco, CA (US);
Assignee:
DEPUY MITEK, LLC, Raynham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/32 (2015.01); C12N 5/077 (2010.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61K 9/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/32 (2013.01); A61K 9/0024 (2013.01); A61L 27/3817 (2013.01); A61L 27/54 (2013.01); C12N 5/0655 (2013.01); A61K 35/12 (2013.01); A61L 2300/252 (2013.01); A61L 2430/02 (2013.01); A61L 2430/06 (2013.01); C12N 2510/00 (2013.01); C12N 2533/74 (2013.01); C12N 2533/76 (2013.01);
Abstract
Systems and methods for modifying the environment of target cell using genetically altered chondrocytes are provided. The genetically engineered chondrocytes can be used to express a therapeutic agent in a subject, including in an environment typically associated with chondrocytes and in an environment not typically associated with chondrocytes.