The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Dec. 11, 2014
Applicant:
Lipopeptide Ab, Stockholm, SE;
Inventors:
Mona Ståhle-Bäckdahl, Stockholm, SE;
Johan Heilborn, Stockholm, SE;
Anders Carlsson, Stockholm, SE;
Conny Bogentoft, Hasselby, SE;
Assignee:
Lipopeptide AB, Stockholm, SE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 9/127 (2006.01); A61K 38/16 (2006.01); C07K 14/47 (2006.01); C12N 5/00 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 9/1272 (2013.01); A61K 38/16 (2013.01); C07K 14/47 (2013.01); C07K 14/4723 (2013.01); C12N 5/0018 (2013.01); C12N 5/0629 (2013.01); C12N 2500/32 (2013.01); C12N 2500/36 (2013.01); Y10S 514/938 (2013.01);
Abstract
Use of the antimicrobial cathelicidin peptide II-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end, for stimulating proliferation of epithelial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.