The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Jul. 30, 2014
Applicants:

The Regents of the University of California, Oakland, CA (US);

Nof Corporation, Shibuya-ku, Tokyo, JP;

Inventors:

Fuyuhiko Tamanoi, Los Angeles, CA (US);

Jie Lu, Los Angeles, CA (US);

Kohei Yoshimura, Kawasaki, JP;

Ohyun Kwon, Los Angeles, CA (US);

Hannah Fiji, Fontana, CA (US);

Masaru Watanabe, Yahaba, JP;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/48 (2006.01); C07D 213/89 (2006.01); A61K 31/402 (2006.01); A61K 31/4418 (2006.01); A61K 9/127 (2006.01); A61K 31/40 (2006.01); A61K 45/06 (2006.01); C07D 207/20 (2006.01); C07D 211/96 (2006.01); A61K 31/216 (2006.01);
U.S. Cl.
CPC ...
A61K 9/127 (2013.01); A61K 31/216 (2013.01); A61K 31/40 (2013.01); A61K 31/402 (2013.01); A61K 31/4418 (2013.01); A61K 45/06 (2013.01); C07D 207/20 (2013.01); C07D 207/48 (2013.01); C07D 211/96 (2013.01); C07D 213/89 (2013.01);
Abstract

The present invention relates, for example, to a liposome, which can be a basic liposome, a transferrin-conjugated liposome, or a pH-sensitive liposome, which encapsulates a compound that specifically inhibits the activity of a protein prenyltransferase, such as a RabGGTase and/or a GGTase I. The liposomes can be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.


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