The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Jul. 16, 2007
Silvia Sihui Chen, Derwood, MD (US);
Xiaofei Qin, Virginia Beach, VA (US);
Jingsong Chen, Virginia Beach, VA (US);
Lloyd Wolfinbarger, Norfolk, VA (US);
Mark Moore, Chesapeake, VA (US);
Rony Thomas, Virginia Beach, VA (US);
Alyce Linthurst Jones, Virginia Beach, VA (US);
Silvia Sihui Chen, Derwood, MD (US);
Xiaofei Qin, Virginia Beach, VA (US);
Jingsong Chen, Virginia Beach, VA (US);
Lloyd Wolfinbarger, Norfolk, VA (US);
Mark Moore, Chesapeake, VA (US);
Rony Thomas, Virginia Beach, VA (US);
Alyce Linthurst Jones, Virginia Beach, VA (US);
LifeNet Health, Virginia Beach, VA (US);
Abstract
The present invention is directed toward recellularizing a devitalized cartilage graft with viable recellularizable cells in vivo, in situ, or in vitro to render the tissue vital. The present invention is also directed toward repairing a cartilage defect and implanting a cartilage graft into a human or animal by crafting a cartilage matrix into individual grafts, disinfecting and cleaning the cartilage graft, applying a pretreatment solution to the cartilage graft, removing cellular debris using an extracting solution to produce a devitalized cartilage graft, recellularizing the devitalized cartilage graft, implanting the cartilage graft into the cartilage defect with or without an insertion device, and sealing the implanted cartilage graft with recipient tissue. The devitalized cartilage graft is optionally stored between the removing cellular debris and the recellularizing steps. The present invention is directed to both recellularized cartilage grafts as well as a process for recellularizing cartilage grafts.