The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Oct. 17, 2008
Fumihiko Ishikawa, Kanagawa, JP;
Yoriko Saito, Kanagawa, JP;
Osamu Ohara, Kanagawa, JP;
Leonard D. Shultz, Bar Harbor, ME (US);
Fumihiko Ishikawa, Kanagawa, JP;
Yoriko Saito, Kanagawa, JP;
Osamu Ohara, Kanagawa, JP;
Leonard D. Shultz, Bar Harbor, ME (US);
RIKEN, Wako, JP;
The Jackson Laboratory, Bar Harbor, ME (US);
Abstract
The invention relates to a method of selectively expanding human leukemic cells in a non-adult NOD/SCID/IL2rgmouse by transplanting a substance containing a leukemic stem cell derived from a human acute myelogenous leukemia patient to the mouse. In addition, the invention relates to screening for a medicament capable of eradicating leukemic stem cell (LSC), consideration of treatment methods suitable for individual patients, identification of a differentially expressed gene and the like, using a mouse with expanded human leukemic cells.