The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2015
Filed:
Dec. 04, 2012
Applicant:
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Inventors:
Yi Feng Zheng, Wilmington, DE (US);
Tie Q. Wei, Wilmington, DE (US);
Assignee:
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61K 31/436 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
G01N 33/9493 (2013.01); A61K 31/436 (2013.01); G01N 33/5308 (2013.01);
Abstract
Compositions are disclosed for releasing an FKBP-binding immunosuppressant drug from endogenous binding substances in a sample suspected of containing the FKBP-binding immunosuppressant drug. The compositions include sirolimus derivatives that are modified with a bulky organic radical in the triene portion of the sirolimus molecule. The compositions may be employed in conjunction with assays for an FKBP-binding immunosuppressant drug in a sample suspected of containing the drug.