The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2015

Filed:

Dec. 19, 2003
Applicants:

Alex Haahr Gouliaev, Vekso Sjaelland, DK;

Anette Holtmann, Ballerup, DK;

Henrik Pedersen, Bagsvaerd, DK;

Thomas Franch, Snekkersten, DK;

Inventors:

Alex Haahr Gouliaev, Vekso Sjaelland, DK;

Anette Holtmann, Ballerup, DK;

Henrik Pedersen, Bagsvaerd, DK;

Thomas Franch, Snekkersten, DK;

Assignee:

Nuevolution A/S, Copenhagen, DK;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C40B 50/00 (2006.01); C40B 20/04 (2006.01); C40B 30/00 (2006.01); C40B 50/10 (2006.01); C12Q 1/68 (2006.01); C07H 21/02 (2006.01); C40B 30/04 (2006.01); C12N 15/10 (2006.01); C40B 40/06 (2006.01); C40B 50/08 (2006.01); C40B 50/04 (2006.01);
U.S. Cl.
CPC ...
C40B 30/04 (2013.01); C12N 15/1068 (2013.01); C40B 20/04 (2013.01); C40B 40/06 (2013.01); C40B 50/08 (2013.01); C40B 50/04 (2013.01); Y10T 436/145555 (2015.01);
Abstract

The present invention is directed to the synthesis of molecules guided by connector polynucleotides (CPNs) capable of hybridizing to complementary connector polynucleotides (CCPNs) harboring at least one functional entity comprising at least one reactive group. At least one of the CCPNs is capable of hybridizing to at least two CPNs. Each CPN will 'call' for one or more CCPNs capable of hybridization to the CPN. Following the formation of a supramolecular hybridization complex comprising a plurality of CPNs and a plurality of CCPNs, the reaction of reactive groups results in the formation of a molecule comprising covalently linked functional entities. The formation of the molecule involves the transfer of functional entities from one or more 'donor CCPNs' to at least one “acceptor CCPN” with which the transferred functional entities were not associated prior to the transfer.


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