The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9120866 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 01, 2015

Filed:

Feb. 24, 2011
Applicants:

Helmut Fiebig, Schwarzenbek, DE;

Andreas Nandy, Hamburg, DE;

Roland Suck, Hamburg, DE;

Oliver Cromwell, Wentorf, DE;

Arnd Petersen, Bad Segeberg, DE;

Wolf-meinhard Becker, Mozen, DE;

Inventors:

Helmut Fiebig, Schwarzenbek, DE;

Andreas Nandy, Hamburg, DE;

Roland Suck, Hamburg, DE;

Oliver Cromwell, Wentorf, DE;

Arnd Petersen, Bad Segeberg, DE;

Wolf-Meinhard Becker, Mozen, DE;

Assignee:

MERCK PATENT GMBH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 1/12 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12P 21/04 (2006.01); C12P 21/06 (2006.01); C07K 14/415 (2006.01); G01N 33/68 (2006.01); A61K 31/7088 (2006.01); A61K 39/36 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/415 (2013.01); A61K 31/7088 (2013.01); A61K 39/36 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); G01N 33/6893 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); G01N 2800/24 (2013.01);
Abstract

The present invention relates to the provision of the genetic sequence of the major grass pollen allergen Phl p 4. The invention also covers fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilized for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for the in vitro and in vivo diagnosis of pollen allergies.


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