The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2015
Filed:
Dec. 13, 2011
Cheng Chen, Plainsboro, NJ (US);
Jongrock Kong, Princeton, NJ (US);
Guy Humphrey, Hillsborough, NJ (US);
Sarah Dolman, Jersey City, NJ (US);
Hongmei LI, Edison, NJ (US);
Matthew T. Tudge, Chatham, NJ (US);
Kelvin Yong, Lyndhurst, NJ (US);
Bangping Xiang, Plainsboro, NJ (US);
Michael Zacuto, Jersey City, NJ (US);
Cheng Chen, Plainsboro, NJ (US);
Jongrock Kong, Princeton, NJ (US);
Guy Humphrey, Hillsborough, NJ (US);
Sarah Dolman, Jersey City, NJ (US);
Hongmei Li, Edison, NJ (US);
Matthew T. Tudge, Chatham, NJ (US);
Kelvin Yong, Lyndhurst, NJ (US);
Bangping Xiang, Plainsboro, NJ (US);
Michael Zacuto, Jersey City, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to macrolactam compounds, intermediates useful in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing and modifying macrolactams. One use of the compounds and methods described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. An example of an HCV inhibitory compound that can be synthesized using the procedures described herein is Compound A and derivative thereof.