The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2015
Filed:
Jan. 27, 2014
Applicants:
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;
Inventors:
Peng Cho Tang, Shanghai, CN;
Hejun Lü, Shanghai, CN;
Hongbo Fei, Shanghai, CN;
Yiqian Chen, Shanghai, CN;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4152 (2006.01); C07D 231/08 (2006.01); C07D 231/46 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); A61K 31/4155 (2006.01); A61K 45/06 (2006.01); C07C 211/05 (2006.01); C07C 211/27 (2006.01); C07C 215/08 (2006.01); C07C 215/10 (2006.01); C07C 215/40 (2006.01); C07C 279/14 (2006.01); C07D 295/027 (2006.01);
U.S. Cl.
CPC ...
C07D 231/46 (2013.01); A61K 31/4152 (2013.01); A61K 31/4155 (2013.01); A61K 45/06 (2013.01); C07C 211/05 (2013.01); C07C 211/27 (2013.01); C07C 215/08 (2013.01); C07C 215/10 (2013.01); C07C 215/40 (2013.01); C07C 279/14 (2013.01); C07D 295/027 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01);
Abstract
The pharmaceutically acceptable salts of bicycle-substituted pyrazolon azo derivatives represented by the general formula (I), their preparation methods, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor. The definitions of substituents in the general formula (I) are the same as the description.