The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2015

Filed:

Jun. 09, 2011
Applicants:

Steven P. Nolan, St Andrews, GB;

Catherine Cazin, St Andrews, GB;

Inventors:

Steven P. Nolan, St Andrews, GB;

Catherine Cazin, St Andrews, GB;

Attorneys:
Int. Cl.
CPC ...
C07B 41/08 (2006.01); C07D 233/02 (2006.01); C07D 233/04 (2006.01); C07D 233/90 (2006.01); C07D 207/04 (2006.01); C07D 207/18 (2006.01); B01J 23/66 (2006.01); B01J 23/72 (2006.01); B01J 31/22 (2006.01); B01J 31/18 (2006.01); B01J 31/24 (2006.01); C07B 59/00 (2006.01); C07D 235/24 (2006.01); C07D 237/24 (2006.01); C07D 249/10 (2006.01); C07D 253/07 (2006.01); C07D 261/18 (2006.01); C07D 263/34 (2006.01); C07D 263/58 (2006.01); C07D 275/03 (2006.01); C07D 277/56 (2006.01); C07D 277/68 (2006.01); C07D 307/68 (2006.01); C07D 473/00 (2006.01); C07F 1/08 (2006.01); C07F 1/10 (2006.01);
U.S. Cl.
CPC ...
C07B 41/08 (2013.01); B01J 31/185 (2013.01); B01J 31/2226 (2013.01); B01J 31/2265 (2013.01); B01J 31/2269 (2013.01); B01J 31/2273 (2013.01); B01J 31/24 (2013.01); C07B 59/002 (2013.01); C07D 233/90 (2013.01); C07D 235/24 (2013.01); C07D 237/24 (2013.01); C07D 249/10 (2013.01); C07D 253/07 (2013.01); C07D 261/18 (2013.01); C07D 263/34 (2013.01); C07D 263/58 (2013.01); C07D 275/03 (2013.01); C07D 277/56 (2013.01); C07D 277/68 (2013.01); C07D 307/68 (2013.01); C07D 473/00 (2013.01); C07F 1/08 (2013.01); C07F 1/10 (2013.01); B01J 2531/16 (2013.01); B01J 2531/17 (2013.01); B01J 2531/18 (2013.01);
Abstract

The use of a complex of the form Z—M—OR in the carboxylation of a substrate is described. The group Z is a two-electron donor ligand, M is a metal and OR is selected from the group consisting of OH, alkoxy and aryloxy. The substrate may be carboxylated at a C—H or N—H bond. The metal M may be copper, silver or gold. The two-electron donor ligand may be a phosphine, a carbene or a phosphite ligand. Also described are methods of manufacture of the complexes and methods for preparing isotopically labelled caboxylic acids and carboxylic acid derivatives.


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