The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2015

Filed:

Oct. 31, 2012
Applicants:

Monika Weber, New Haven, CT (US);

Mark A. Reed, Monroe, CT (US);

Inventors:

Monika Weber, Wroclaw, PL;

Siu Lung Lo, Mid-levels, HK;

Hazael Fabrizio Montanaro Ochoa, Asuncion, PY;

Christopher Daniel Yerino, New Haven, CT (US);

Mark A. Reed, Monroe, CT (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); B03C 5/02 (2006.01); G01N 33/487 (2006.01); B03C 5/00 (2006.01); B01L 3/00 (2006.01); G01N 27/414 (2006.01);
U.S. Cl.
CPC ...
B03C 5/024 (2013.01); B01L 3/502753 (2013.01); B03C 5/005 (2013.01); G01N 33/487 (2013.01); B01L 2300/0874 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0424 (2013.01); B01L 2400/0487 (2013.01); B03C 2201/26 (2013.01); G01N 27/4145 (2013.01);
Abstract

An apparatus and method for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. Species movement is caused by a module array imparting opposing dielectrophoretic forces. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The Clausius-Mossotti factor of the analyte is changed by flushing the analyte with a reference solution, which causes a negative dielectrophoretic force to facilitate release of the analyte. A field effect nanowire or nanoribbon sensor detects the analyte after capture.


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