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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9119884 B1

PDFFull Text
Date of Patent:
Sep. 01, 2015

Filed:

Jan. 19, 2012

Llp2a-bisphosphonate conjugates for osteoporosis treatment

Applicants:

Kit S. Lam, Oakland, CA (US);

Ruiwu Liu, Oakland, CA (US);

Wei Yao, Oakland, CA (US);

Nancy Lane, Oakland, CA (US);

Inventors:

Kit S. Lam, Oakland, CA (US);

Ruiwu Liu, Oakland, CA (US);

Wei Yao, Oakland, CA (US);

Nancy Lane, Oakland, CA (US);

Assignee:

The Regents of the University of California, Oakland, CA (US);

Attorney:

Kilpatrick Townsend Stockton LLP

Primary Examiner:

James H Alstrum Acevedo

Assistant Examiner:

Thea D' Ambrosio

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 19/08 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61K 38/10 (2006.01); A61K 38/16 (2006.01); A61K 38/08 (2006.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); A61K 38/04 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 47/48 (2006.01); A61K 31/663 (2006.01); C07K 7/06 (2006.01); A61K 31/66 (2006.01); C07F 9/02 (2006.01); A61K 31/00 (2006.01); A61K 31/661 (2006.01); C07K 5/09 (2006.01); C07K 5/103 (2006.01); C07K 5/107 (2006.01); C07K 5/11 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 31/00 (2013.01); A61K 31/66 (2013.01); A61K 31/661 (2013.01); A61K 31/663 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 47/48084 (2013.01); C07F 9/02 (2013.01); C07K 5/0817 (2013.01); C07K 5/101 (2013.01); C07K 5/1016 (2013.01); C07K 5/1019 (2013.01); C07K 7/06 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention provides compounds and pharmaceutical compositions of a peptidomimetic ligand, e.g. LLP2A, conjugated with a bisphosphonate drug, e.g. Alendronate. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of osteoporosis and for the promotion of bone growth due to their specificity for the αβintegrin on mesenchymal stem cells and for the surface of bone.

Find Patent Forward Citations

Lam, Kit. (2015). Llp2a-bisphosphonate conjugates for osteoporosis treatment (U.S. Patent No. 9119884). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9119884

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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