The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2015

Filed:

Nov. 30, 2011
Applicants:

Mario Pablo Estrada Garcia, La Habana, CU;

Juna Maria Lugo Gonzalez, Artemisa, CU;

Yamila Carpio Gonzalez, La Habana, CU;

Carolina Tafalla Piñeiro, Madrid, ES;

Inventors:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/08 (2006.01); A61K 31/7056 (2006.01); A61K 38/22 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 38/22 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 9/5153 (2013.01); A61K 31/7056 (2013.01); A61K 38/2278 (2013.01);
Abstract

The present invention relates to the use of pituitary adenylate cyclase activating polypeptide (PACAP) in the treatment of viral diseases and infectious diseases caused by viruses in aquatic organisms. PACAP, alone or combined with an antiviral molecule, demonstrated its effectiveness by increasing the survival of fish or crustaceans infected by viruses when it was administered orally, by injection or by immersion baths. Furthermore, it was observed that treated organisms keep or increase its weight as compared to infected and non-treated organisms. PACAP or PACAP-containing combinations decreased the viral load in tissues and organs susceptible to viral infections as it was determined by RT-PCR.


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