The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2015

Filed:

Aug. 06, 2013
Applicants:

Kangwon National University University-industry Cooperation Foundation, Gangwon-Do, KR;

Amogreentech Co., Ltd., Gyeonggi-do, KR;

Inventors:

Kwon-Soo Ha, Gangwon-Do, KR;

Young-Cheol Lim, Gangwon-Do, KR;

Assignee:

AMOGREENTECH CO., LTD., Gyeonggi-do, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/00 (2006.01); A61P 3/10 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/17 (2013.01); A61K 38/1703 (2013.01);
Abstract

Disclosed are a method and composition for the prevention or treatment of diabetic angiogenesis impairment or diabetic wound-healing impairment, using C-peptide. Found to be able to induce angiogenesis through chemotactic migration of endothelial cells, cell migration to wounded areas, capillary-like network formation, and extracellular signal-regulated kinases 1/2 and Akt phosphorylation and nitric oxide production, C-peptide has prophylactic or therapeutic applications in a broad spectrum of various diabetic complications including diabetic angiogenesis impairment.


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