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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9116144 B1

PDFFull Text
Date of Patent:
Aug. 25, 2015

Filed:

Dec. 10, 2012

Methods for preparing thermally responsive cell culture surfaces

Applicant:

Innovative Surface Technologies, Inc., St. Paul, MN (US);

Inventors:

Tahmina Naqvi, Blaine, MN (US);

Jie Wen, St. Johns, FL (US);

Patrick Guire, Hopkins, MN (US);

Assignee:

INNOVATIVE SURFACE TECHNOLOGIES, INC., St. Paul, MN (US);

Attorneys:

Weaver Legal and Consulting LLC

Karrie G. Weaver

Primary Examiner:

Jim Ketter

Assistant Examiner:

Antonio Galisteo Gonzalez

Int. Cl.
CPC ...
G01N 33/48 (2006.01); A61L 27/16 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 29/04 (2006.01); A61L 29/08 (2006.01); A61L 29/14 (2006.01); A61L 29/16 (2006.01); A61L 31/04 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); C12M 1/00 (2006.01); D01D 5/00 (2006.01); D01F 1/10 (2006.01); D01F 6/22 (2006.01); D01F 6/26 (2006.01); D01F 6/62 (2006.01); D06M 15/285 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48 (2013.01); A61L 27/16 (2013.01); A61L 27/34 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 29/041 (2013.01); A61L 29/085 (2013.01); A61L 29/14 (2013.01); A61L 29/16 (2013.01); A61L 31/048 (2013.01); A61L 31/10 (2013.01); A61L 31/14 (2013.01); A61L 31/16 (2013.01); C12M 23/20 (2013.01); D01D 5/0007 (2013.01); D01F 1/10 (2013.01); D01F 6/22 (2013.01); D01F 6/26 (2013.01); D01F 6/625 (2013.01); D06M 15/285 (2013.01); A61L 2300/00 (2013.01); D06M 2400/01 (2013.01);
Abstract

A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.

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