The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Sep. 17, 2014
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Jolene Bradford, Eugene, OR (US);
Ching-Ying Cheung, San Ramon, CA (US);
Shih-Jung Huang, Eugene, OR (US);
Patrick Pinson, Eugene, OR (US);
Stephen Yue, Eugene, OR (US);
Assignee:
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/00 (2006.01); C12Q 1/68 (2006.01); C07D 215/10 (2006.01); C07D 215/227 (2006.01); C07D 277/72 (2006.01); C07D 277/74 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C07D 215/10 (2013.01); C07D 215/227 (2013.01); C07D 277/72 (2013.01); C07D 277/74 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); G01N 21/6486 (2013.01);
Abstract
Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.