The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Mar. 23, 2013
Applicant:
Rg Biopharma, Llc, San Diego, CA (US);
Inventors:
Ruth A Gjerset, San Diego, CA (US);
Keya Bandyopadhyay, San Diego, CA (US);
Assignee:
RG BioPHARMA LLC, San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C12Q 1/533 (2006.01); A61K 31/4164 (2006.01); A61K 31/4375 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/533 (2013.01); A61K 31/4164 (2013.01); A61K 31/4375 (2013.01); C12Q 1/6886 (2013.01); G01N 33/574 (2013.01); C12Q 2600/106 (2013.01); G01N 2333/99 (2013.01); G01N 2800/52 (2013.01);
Abstract
Disclosed herein are methods and compositions for determining the sensitivity or enhancing the sensitivity of cells to the effects of topoisomerase I inhibitors. Also disclosed are methods and compositions for inducing cell death, apoptosis and/or growth arrest which may be used for tumor suppression.