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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9115212 B1

PDFFull Text
Date of Patent:
Aug. 25, 2015

Filed:

Jan. 31, 2013

Bifunctional peptide

Applicants:

Regentis International, Reims, FR;

Universite DE Reims Champagne Ardenne, Reims, FR;

Centre National DE LA Recherche Scientifique, Paris Cedex, FR;

Inventors:

William Hornebeck, Reims, FR;

Joan Attia, Reims, FR;

Sandrine Lorimier, Reims, FR;

Frank Antonicelli, Witry-les-Reims, FR;

Assignees:

REGENTIS INTERNATIONAL, Reims, FR;

UNIVERSITE DE REIMS CHAMPAGNE ARDENNE, Reims, FR;

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris Cedex, FR;

Attorneys:

Andrew W. Chu

Craft Chu PLLC

Primary Examiner:

Marcela M Cordero Garcia

Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 14/81 (2006.01); A61Q 19/08 (2006.01); C07K 14/78 (2006.01); C07K 5/083 (2006.01); C07K 5/11 (2006.01); A61K 8/64 (2006.01);
U.S. Cl.
CPC ...
C07K 14/8146 (2013.01); A61K 8/64 (2013.01); A61Q 19/08 (2013.01); C07K 5/0804 (2013.01); C07K 5/1019 (2013.01); C07K 14/78 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/50 (2013.01); C07K 2319/75 (2013.01);
Abstract

The bifunctional peptide is capable of activating collagen synthesis and inhibiting the production of matrix metallo-proteinases. The peptide has a sequence including three peptide parts A, B and C. The first peptide part A corresponds to a hexapeptide repeated at least three times, the part A being capable of bonding to a receptor elastin-binding protein in order to stimulate collagen synthesis. The second peptide part B corresponds to a tetrapeptide capable of acting as a competitive inhibitor of urokinase protease and of being cleaved by said protease. The third peptide part C corresponds to a tripeptide occupying at least one active site of the matrix metallo-proteinases in order to enable inhibition of the proteinases. The present invention further concerns a cosmetic and/or pharmaceutical composition incorporating the bifunctional peptide.

Find Patent Forward Citations

Hornebeck, William. (2015). Bifunctional peptide (U.S. Patent No. 9115212). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9115212

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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