The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Mar. 01, 2011
Ming-jiu Chen, Shrewsbury, MA (US);
Chung-ming Hsieh, Newton, MA (US);
Jijie Gu, Shrewsbury, MA (US);
Susan E. Morgan-lappe, Chicago, IL (US);
Yingchun LI, Buffalo Grove, IL (US);
Ming-Jiu Chen, Shrewsbury, MA (US);
Chung-Ming Hsieh, Newton, MA (US);
Jijie Gu, Shrewsbury, MA (US);
Susan E. Morgan-Lappe, Chicago, IL (US);
Yingchun Li, Buffalo Grove, IL (US);
ABBVIE INC., North Chicago, IL (US);
Abstract
DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.