The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Feb. 28, 2014
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Kimberly M. Bonger, Nijmegen, NL;
Rishi Rakhit, Menlo Park, CA (US);
Thomas J. Wandless, Menlo Park, CA (US);
Assignee:
The Board of Trustees of The Leland Stanford Junior University, Palo Alto, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12P 21/04 (2006.01); C12N 5/07 (2010.01); C12N 5/10 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); C07K 7/08 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
C07K 14/001 (2013.01); C07K 7/08 (2013.01); C07K 14/005 (2013.01);
Abstract
Disclosed herein are a light-inducible system and method for rapidly and reversibly modulating protein stability and function. This system and method employs conditionally stable protein domains that regulate the degradation of a fusion protein depending upon the presence or absence of a particular light source.