The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Jan. 30, 2013
Applicant:
Sanford-burnham Medical Research Institute, La Jolla, CA (US);
Inventors:
Erkki Ruoslahti, Buellton, CA (US);
Kazuki Sugahara, Goleta, CA (US);
Tambet Teesalu, Goleta, CA (US);
Assignee:
Sanford-Burnham Medical Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 7/64 (2006.01); A61K 38/08 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01); C07K 5/083 (2006.01); C07K 5/103 (2006.01); C07K 5/11 (2006.01); A61K 51/08 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 47/48246 (2013.01); A61K 49/0002 (2013.01); A61K 49/0043 (2013.01); A61K 49/0056 (2013.01); A61K 49/0082 (2013.01); A61K 51/082 (2013.01); C07K 5/081 (2013.01); C07K 5/1013 (2013.01); C07K 5/1019 (2013.01); C07K 7/64 (2013.01);
Abstract
Disclosed are compositions and methods useful for targeting tissue undergoing angiogenesis or to cells or tissue expressing αv integrins. The compositions and methods are based on peptide sequences that selectively bind to and home to tissue undergoing angiogenesis or to cells or tissue expressing αv integrins in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tissue experiencing angiogenesis or to cells or tissue expressing αv integrins.