The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2015

Filed:

Mar. 18, 2014
Applicant:

Anthem Biosciences Pvt. Ltd, Bangalore, KR;

Inventors:

Tom Thomas Puthiaparampil, Bangalore, IN;

Ganesh Sambasivam, Bangalore, IN;

Rajulu Gavara Govinda, Bangalore, IN;

Ravindra Chandrappa Koramangala, Bangalore, IN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/00 (2006.01); C07D 471/04 (2006.01); C07C 205/56 (2006.01); C07C 201/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07C 201/08 (2013.01); C07C 205/56 (2013.01);
Abstract

Synthesis of the novel compound 3 (3-(5-substituted Oxy-2,4-dinitro-phenyl)-2-oxo-propionic acid ester) to make Pyrroloquinoline quinone (PQQ) and using it for pharmaceutical purposes is described. More specifically, this disclosure relates to synthesizing the PQQ in an efficient method by using a novel intermediate Formula 1 resulting in a shorter process and higher yield of PQQ. A unique process to make sodium compound of PQQ using either sodium hydroxide and/or sodium carbonate is also shown.


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