IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9115127 B1

PDFFull Text
Date of Patent:
Aug. 25, 2015

Filed:

Jul. 28, 2011

Benzimidazole and azabenzimidazole compounds that inhibit anaplastic lymphoma kinase

Applicants:

Christiane M. Boezio, Somerville, MA (US);

Alan C. Cheng, San Francisco, CA (US);

Deborah Choquette, Medford, MA (US);

Richard T. Lewis, Framingham, MA (US);

Michele H. Potashman, Cambridge, MA (US);

Karina Romero, Arlington, MA (US);

John C. Stellwagen, Beverly, MA (US);

Douglas A. Whittington, Waltham, MA (US);

Inventors:

Christiane M. Boezio, Somerville, MA (US);

Alan C. Cheng, San Francisco, CA (US);

Deborah Choquette, Medford, MA (US);

Richard T. Lewis, Framingham, MA (US);

Michele H. Potashman, Cambridge, MA (US);

Karina Romero, Arlington, MA (US);

John C. Stellwagen, Beverly, MA (US);

Douglas A. Whittington, Waltham, MA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorneys:

Choate, Hall & Stewart LLP

Brenda Herschbach Jarrell

Kristen C. Buteau

Primary Examiner:

Sreeni Padmanabhan

Assistant Examiner:

Irina Neagu

Int. Cl.
CPC ...
C07D 235/30 (2006.01); C07D 235/32 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/08 (2006.01); C07D 403/14 (2006.01); C07D 417/04 (2006.01); C07D 413/04 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01); C07D 417/06 (2006.01); C07D 487/04 (2006.01); C07D 401/10 (2006.01); C07D 413/10 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 417/12 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 235/30 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/08 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds of Formula (I) are useful inhibitors of anaplastic lymphoma kinase. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.

Find Patent Forward Citations

Loading…