The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Jan. 13, 2011
Jiaqiang Cai, Newhouse, GB;
David Jonathan Bennett, West Point, PA (US);
Philip Stephen Jones, Newhouse, GB;
Jiaqiang Cai, Newhouse, GB;
David Jonathan Bennett, West Point, PA (US);
Philip Stephen Jones, Newhouse, GB;
Merck Sharp & Dohme B.V., Haarlem, NL;
Abstract
The invention relates to 1H-[1,2,3]triazolo[4,5-c]pyridine-4-carbonitrile derived Cathepsin S inhibitors of Formula (I), wherein Ris H or (C)alkyl; Ris halogen or (C)alkyl, optionally substituted with one or more halogens; n is 1-3; X is O or CH; U, V and W are CH; or one of U, V and W is N; Y is a group capable of interacting with the S. . . Ssubstites of the active site of Cathepsin S; or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such as atherosclerosis, obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer, and chronic pain, such as neuropathic pain.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile