The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Jan. 21, 2014
Academia Sinica, Taipei, TW;
National Taiwan University, Taipei, TW;
Jung-Hsin Lin, New Taipei, TW;
Ching-Chow Chen, Taipei, TW;
Jim-Min Fang, Taipei, TW;
Jhih-Bin Chen, Lukang Township, Changhua County, TW;
Ting-Rong Chern, Taipei, TW;
Tzu-Tang Wei, Taipei, TW;
Academia Sinica, Taipei, TW;
National Taiwan University, Taipei, TW;
Abstract
Disclosed herein are novel compounds of formula (I), and uses thereof. The compounds of Formula (I) are inhibitors of histone deacetylases (HDACs) and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR). Also provided are methods of using the compounds of Formula (I) for inhibiting the activity of HDACs and HMGR, treating diseases associated with HDACs or HMGR (e.g., cancer, hypercholesterolemia, an acute or chronic inflammatory disease, autoimmune disease, allergic disease, pathogen infection, neurodegenerative disease, or a disease associated with oxidative stress,