The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2015

Filed:

Jul. 11, 2013
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Monique Bodil van Niel, Harlow, GB;

Benjamin Fauber, San Francisco, CA (US);

Simon Gaines, Harlow, GB;

Alberto Gobbi, San Francisco, CA (US);

Olivier Rene, San Francisco, CA (US);

David Vesey, Harlow, GB;

Stuart Ward, Harlow, GB;

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/10 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 279/02 (2006.01); C07D 281/02 (2006.01); C07D 291/02 (2006.01); C07D 295/185 (2006.01); C07D 491/10 (2006.01); C07D 513/10 (2006.01); A61K 31/541 (2006.01); A61P 19/02 (2006.01); C07D 451/14 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01); C07D 487/08 (2006.01); C07D 275/02 (2006.01); C07D 498/10 (2006.01); C07D 515/12 (2006.01);
U.S. Cl.
CPC ...
C07D 295/185 (2013.01); C07D 275/02 (2013.01); C07D 279/02 (2013.01); C07D 281/02 (2013.01); C07D 291/02 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 451/14 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 491/10 (2013.01); C07D 498/10 (2013.01); C07D 513/10 (2013.01); C07D 515/12 (2013.01);
Abstract

Compounds of the formula I: or pharmaceutically acceptable salts thereof,wherein m, n, p, q, r, A, W, X, X, X, X, Y, Z, R, R, R, R, R, R, R, R, R, R, R, and Rare as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.


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