The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Apr. 25, 2013
Applicant:
Janssen Pharmaceutica, NV, Beerse, BE;
Inventors:
Dominique Jean-Pierre Mabire, Val de Reuil, FR;
Jerome Emile Georges Guillemont, Val de Reuil, FR;
Jacobus Alphonsus Josephus van Dun, Beerse, BE;
Maria Victorina Francisca Somers, Beerse, BE;
Walter Boudewijn Leopold Wouters, Beerse, BE;
Assignee:
Janssen Pharmaceutica, NV, , BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 221/12 (2006.01); C07D 215/227 (2006.01); C07D 241/44 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 405/06 (2006.01); C07D 405/14 (2006.01); C07D 407/06 (2006.01); C07D 409/12 (2006.01); C07D 401/10 (2006.01); C07D 405/10 (2006.01);
U.S. Cl.
CPC ...
C07D 215/227 (2013.01); C07D 241/44 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 405/06 (2013.01); C07D 405/10 (2013.01); C07D 405/14 (2013.01); C07D 407/06 (2013.01); C07D 409/12 (2013.01);
Abstract
The present invention provides compounds of formula (I) and compounds of formula (VII-a) as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitors wherein n, R, R, R, R, R, R, R, R, Rand X have defined meanings.