The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Aug. 31, 2011
Ivor T. Knight, Arlington, VA (US);
Kenton C. Hasson, Germantown, MD (US);
Johnathan S. Coursey, Germantown, MD (US);
Hongye Liang, Clarksville, MD (US);
Sami Kanderian, Germantown, MD (US);
Gregory H. Owen, Clarksburg, MD (US);
Weidong Cao, N. Potomac, MD (US);
Ying-xin Wang, Rockville, MD (US);
Scott Corey, Hydes, MD (US);
Ben Lane, Hydes, MD (US);
Conrad Laskowski, Baltimore, MD (US);
Alex Flamm, Baltimore, MD (US);
Brian Murphy, Baltimore, MD (US);
Eric Schneider, Catonsville, MD (US);
Takayoshi Hanagata, Newport News, VA (US);
Hiroshi Inoue, Rockville, MD (US);
Shulin Zeng, Gaithersburg, MD (US);
Brian Bean, Baltimore, MD (US);
Franklin Regan, Baltimore, MD (US);
Ivor T. Knight, Arlington, VA (US);
Kenton C. Hasson, Germantown, MD (US);
Johnathan S. Coursey, Germantown, MD (US);
Hongye Liang, Clarksville, MD (US);
Sami Kanderian, Germantown, MD (US);
Gregory H. Owen, Clarksburg, MD (US);
Weidong Cao, N. Potomac, MD (US);
Ying-Xin Wang, Rockville, MD (US);
Scott Corey, Hydes, MD (US);
Ben Lane, Hydes, MD (US);
Conrad Laskowski, Baltimore, MD (US);
Alex Flamm, Baltimore, MD (US);
Brian Murphy, Baltimore, MD (US);
Eric Schneider, Catonsville, MD (US);
Takayoshi Hanagata, Newport News, VA (US);
Hiroshi Inoue, Rockville, MD (US);
Shulin Zeng, Gaithersburg, MD (US);
Brian Bean, Baltimore, MD (US);
Franklin Regan, Baltimore, MD (US);
Canon U.S. Life Sciences, Inc., Rockville, MD (US);
Abstract
The present invention relates to systems and methods for the real time processing of nucleic acid during polymerase chain reaction (PCR) and thermal melt applications. According to an aspect of the invention, a system for the rapid serial processing of multiple nucleic acid assays is provided. In one embodiment, the system includes, but is not limited to: a microfluidic cartridge having microfluidic (flow-through) channels, a fluorescence imaging system, a temperature measurement and control system; a pressure measurement and control system for applying variable pneumatic pressures to the microfluidic cartridge; a storage device for holding multiple reagents (e.g., a well-plate); a liquid handling system comprising at least one robotic pipettor for aspirating, mixing, and dispensing reagent mixtures to the microfluidic cartridge; systems for data storage, processing, and output; and a system controller to coordinate the various devices and functions.