The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Nov. 19, 2012
The University of Tokyo, Tokyo, JP;
National University Corporation Tokyo Medical and Dental University, Tokyo, JP;
Nanocarrier Co., Ltd., Kashiwa-shi, JP;
Kazunori Kataoka, Tokyo, JP;
Takehiko Ishii, Tokyo, JP;
Mitsuru Naito, Tokyo, JP;
Akira Matsumoto, Tokyo, JP;
Yasuki Kato, Kashiwa, JP;
THE UNIVERSITY OF TOKYO, Tokyo, JP;
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, Tokyo, JP;
NANOCARRIER CO., LTD., Kashiwa, JP;
Abstract
A block copolymer includes a polyamino acid chain segment and a hydrophilic polymer chain segment. The polyamino acid chain segment includes at least one amino acid residue having a side chain that contains a cationic group and at least one amino acid residue having a side chain that contains a substituted phenylboronic acid group. In the substituted phenylboronic acid group, at least one hydrogen of the phenyl ring is substituted so that the phenylboronic acid group has a pKa of less than 8. Such a block copolymer serves as a carrier that simultaneously imparts stability to a biotechnology-based drug in blood and provides suitable drug-releasing properties of the drug at an affected area.